Oxymetazoline: Difference between revisions
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==Contraindications== | ==Contraindications== | ||
*Allergy to class/drug | *Allergy to class/drug | ||
==Warnings/Precautions== | |||
*Use with caution in patients with hypertension, heart failure or coronary artery disease | |||
*Use with caution in patients with diabetes mellitus | |||
*Use with caution in patients with hyperthyroidism | |||
*Use with caution in patients with benign prostatic hyperplasia | |||
==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*Rebound nasal congestion may occur with extended use | |||
===Common=== | ===Common=== | ||
==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Half-life: not available | ||
*Metabolism: | *Metabolism: not available | ||
*Excretion: | *Excretion: not available | ||
==Mechanism of Action== | ==Mechanism of Action== | ||
*Stimulates α-adrenergic recepter in arterioles of nasal mucosa, produce vasoconstriction | |||
==Comments== | ==Comments== |
Revision as of 01:13, 24 July 2017
Administration
- Type: Decongestant; Adrenergic Agonist Agent; Imidazoline derivative
- Dosage Forms: Solution; Nasal spray
- Routes of Administration: Intranasal
- Common Trade Names: 12-Hour Nasal Relieve Spray, Afrin, Mucinex, Distran, Neo-synephrine
Adult Dosing
- Instill 2-3 sprays for each nostrils twice daily for ≤3 days
Pediatric Dosing
- Children ≥6 years: Instill 2-3 sprays for each nostrils twice daily for ≤3 days
Special Populations
- Pregnancy Rating: Safety during pregnancy has not been studied.
- Lactation risk: Not available
Renal Dosing
- Adult: Not needed
- Pediatric: Not needed
Hepatic Dosing
- Adult: Not needed
- Pediatric: Not needed
Contraindications
- Allergy to class/drug
Warnings/Precautions
- Use with caution in patients with hypertension, heart failure or coronary artery disease
- Use with caution in patients with diabetes mellitus
- Use with caution in patients with hyperthyroidism
- Use with caution in patients with benign prostatic hyperplasia
Adverse Reactions
Serious
- Rebound nasal congestion may occur with extended use
Common
Pharmacology
- Half-life: not available
- Metabolism: not available
- Excretion: not available
Mechanism of Action
- Stimulates α-adrenergic recepter in arterioles of nasal mucosa, produce vasoconstriction