Difference between revisions of "Oxymetazoline"

(Created page with "==Administration== *Type: *Dosage Forms: *Routes of Administration: *Common Trade Names: ==Adult Dosing== ==Pediatric Dosing== ==Special Populations== *Drug Ratings in...")
 
(Text replacement - "alpha" to "α")
(9 intermediate revisions by one other user not shown)
Line 1: Line 1:
 
==Administration==
 
==Administration==
*Type:  
+
*Type: Decongestant; Adrenergic Agonist Agent; Imidazoline derivative
*Dosage Forms:
+
*Dosage Forms: Solution; Nasal spray
*Routes of Administration:
+
*Routes of Administration: Intranasal
*Common Trade Names:  
+
*Common Trade Names: 12-Hour Nasal Relieve Spray, Afrin, Mucinex, Distran, Neo-synephrine
  
 
==Adult Dosing==
 
==Adult Dosing==
 +
*Instill 2-3 sprays for each nostrils twice daily for ≤3 days
  
 
==Pediatric Dosing==
 
==Pediatric Dosing==
 +
*Children ≥6 years: Instill 2-3 sprays for each nostrils twice daily for ≤3 days
  
 
==Special Populations==
 
==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]:
+
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: Safety during pregnancy has not been studied.
*[[Lactation risk categories|Lactation risk]]:
+
*[[Lactation risk categories|Lactation risk]]: Not available
 
===Renal Dosing===
 
===Renal Dosing===
*Adult:
+
*Adult: Not needed
*Pediatric:
+
*Pediatric: Not needed
 
===Hepatic Dosing===
 
===Hepatic Dosing===
*Adult:
+
*Adult: Not needed
*Pediatric:
+
*Pediatric: Not needed
  
 
==Contraindications==
 
==Contraindications==
 
*Allergy to class/drug
 
*Allergy to class/drug
 +
==Warnings/Precautions==
 +
*Use with caution in patients with hypertension, heart failure or coronary artery disease
 +
*Use with caution in patients with diabetes mellitus
 +
*Use with caution in patients with hyperthyroidism
 +
*Use with caution in patients with benign prostatic hyperplasia
  
 
==Adverse Reactions==
 
==Adverse Reactions==
 
===Serious===
 
===Serious===
 +
*Rebound nasal congestion may occur with extended use
  
 
===Common===
 
===Common===
  
 
==Pharmacology==
 
==Pharmacology==
*Half-life:  
+
*Half-life: not available
*Metabolism:  
+
*Metabolism: not available
*Excretion:  
+
*Excretion: not available
  
 
==Mechanism of Action==
 
==Mechanism of Action==
 +
*Stimulates α-adrenergic recepter in arterioles of nasal mucosa, produce vasoconstriction
  
 
==Comments==
 
==Comments==

Revision as of 01:13, 24 July 2017

Administration

  • Type: Decongestant; Adrenergic Agonist Agent; Imidazoline derivative
  • Dosage Forms: Solution; Nasal spray
  • Routes of Administration: Intranasal
  • Common Trade Names: 12-Hour Nasal Relieve Spray, Afrin, Mucinex, Distran, Neo-synephrine

Adult Dosing

  • Instill 2-3 sprays for each nostrils twice daily for ≤3 days

Pediatric Dosing

  • Children ≥6 years: Instill 2-3 sprays for each nostrils twice daily for ≤3 days

Special Populations

Renal Dosing

  • Adult: Not needed
  • Pediatric: Not needed

Hepatic Dosing

  • Adult: Not needed
  • Pediatric: Not needed

Contraindications

  • Allergy to class/drug

Warnings/Precautions

  • Use with caution in patients with hypertension, heart failure or coronary artery disease
  • Use with caution in patients with diabetes mellitus
  • Use with caution in patients with hyperthyroidism
  • Use with caution in patients with benign prostatic hyperplasia

Adverse Reactions

Serious

  • Rebound nasal congestion may occur with extended use

Common

Pharmacology

  • Half-life: not available
  • Metabolism: not available
  • Excretion: not available

Mechanism of Action

  • Stimulates α-adrenergic recepter in arterioles of nasal mucosa, produce vasoconstriction

Comments

See Also

References