Opioid withdrawal: Difference between revisions

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==See Also==
==See Also==
*[[Neonatal abstinence syndrome]]
*[[Neonatal abstinence syndrome]]
*[[Opioid toxicity]]


==Source==
==Source==

Revision as of 16:16, 12 March 2015

Background

  • Uncomfortable but not life-threatening
    • only life-threatening in neonates
  • Onset is 6-12hr after last heroin use, within 30hr after last methadone use

Clinical Presentation

  • Onset: within hours of cessation

Early symptoms

  • Agitation
  • Anxiety
  • Muscle aches
  • Increased tearing
  • Insomnia
  • Runny nose
  • Sweating
  • Yawning
  • Skin-Crawling

Late symptoms

Workup

  • Normally a clinical diagnosis

Differential Diagnosis

Treatment

  1. Clonidine
    • 5mcg/kg PO (as long as SBP >90)
  2. Hydroxyzine
    • 50-100mg PO QID x5d
  3. Antiemetics
  4. Antidiarrheals
  5. NSAIDS
  6. PO/IV hydration

See Also

Source

  • Tintinalli