Opioid withdrawal: Difference between revisions
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#Antiemetics | #Antiemetics | ||
#Antidiarrheals | #Antidiarrheals | ||
#NSAIDS | |||
#PO/IV hydration | |||
==Source== | ==Source== |
Revision as of 22:08, 21 September 2013
Background
- Uncomfortable but not life-threatening
- Onset is 6-12hr after last heroin use, within 30hr after last methadone use
Clinical Features
- Onset: within hours of cessation
- Peak effects: 36-72hr
- Anxiety
- Craving
- Yawning
- Rhinorrhea
- Diaphoresis
- Onset: 12hr after cessation
- Peak effects: 72hr
- Tremor
- Piloerection
- Mydriasis
- Irritability
- Onset: 24-36hr after cessation
- Peak effects: 72hr
- Muscle spasm
- Abd pain
- N/V/D
Treatment
- Clonidine
- 5mcg/kg PO (as long as SBP >90)
- Hydroxyzine
- 50-100mg PO QID x5d
- Antiemetics
- Antidiarrheals
- NSAIDS
- PO/IV hydration
Source
- Tintinalli