Nitroglycerin

Revision as of 22:22, 5 April 2015 by Dx316gol (talk | contribs) (special populations)

General

  • Type: stimulates cGMP production causing vascular smooth muscle relaxation
  • Dosage Forms: SL, IV
  • Common Trade Names: Nitrolingual, NitroMist, Nitrostat

Adult Dosing

  • Angina, Acute: 0.3 - 0.6 mg SL q5min x 3 doses max
  • HTN/CHF: 5-200 mcg/min IV, start 5 mcg/min IV

Pediatric Dosing

HTN/CHF: 1-5 mcg/kg/min IV, start 0.25-0.5 mcg/kg/min, max: 20 mcg/kg/min

Special Populations

  • Pregnancy Rating: C
  • Lactation: safety unknown
  • Renal Dosing
    • Adult: no adjustment
    • Pediatric: no adjustment
  • Hepatic Dosing
    • Adult: not defined
    • Pediatric: not defined

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

Sources