Difference between revisions of "Mitral valve prolapse"

(Physical exam)
Line 12: Line 12:
*Mid-systolic click
*Mid-systolic click
*Late systolic murmur, crescendo into S2
*Late systolic murmur, crescendo into S2
*Assoc. with pes excavatum, scoliosis, low body weight, Marfanoid
*May have associated physical features:
**Pectus excavatum
**Low body weight
**Marfanoid habitus

Revision as of 22:00, 12 March 2019


  • 1 or more mitral valve leaflets bow into left atrium during systole
  • Most common valve disease in industrial countries (2.4% of pop.)
  • Myxomatous degeneration from connective tissue disorder


  • Studies failed to demonstrate that chest pain, anxiety, or palpitations are associated with MVP
  • Symptoms related to autonomic dysfunction: fatigue, anxiety, exercise intolerance
  • If progresses to MR, CHF symptoms

Physical exam

  • Mid-systolic click
  • Late systolic murmur, crescendo into S2
  • May have associated physical features:
    • Pectus excavatum
    • Scoliosis
    • Low body weight
    • Marfanoid habitus


  • Echocardiogram
  • ECG can show nonspecific changes or arrhythmias
  • CXR usually normal

Differential Diagnosis

Valvular Emergencies


  • Aymptomatic
    • None
  • Symptoms of autonomic dysfunction
  • Signs of progression to MR
    • Early surgical repair
  • Neuro sequelae
  • Click / Murmur



  • Thakar, B. Mitral Valve Prolapse. Medscape 2015.