Difference between revisions of "Methylphenidate"
ClaireLewis (talk | contribs) (Created page with "==Administration== *Type: Stimulant *Dosage Forms: *Routes of Administration: PO *Common Trade Names: Ritalin, Concerta ==Adult Dosing== *20-60 mg daily in 2-3 divided doses...") |
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==Special Populations== | ==Special Populations== | ||
===[[Drug pregnancy categories|Pregnancy Rating]]=== | ===[[Drug pregnancy categories|Pregnancy Rating]]=== | ||
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===Common=== | ===Common=== | ||
*Decreased appetite, weight loss, poor weight gain/growth suppression | *Decreased appetite, weight loss, poor weight gain/growth suppression | ||
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*[[Insomnia]], anxiety/restlessness/agitation | *[[Insomnia]], anxiety/restlessness/agitation | ||
*[[Headache]], [[dizziness]], tremor, dyskinesia | *[[Headache]], [[dizziness]], tremor, dyskinesia | ||
Latest revision as of 23:24, 22 September 2019
Contents
Administration
- Type: Stimulant
- Dosage Forms:
- Routes of Administration: PO
- Common Trade Names: Ritalin, Concerta
Adult Dosing
- 20-60 mg daily in 2-3 divided doses
Pediatric Dosing
- >6yo: 5-60mg daily in divided doses
Special Populations
Pregnancy Rating
- Category B
Lactation risk
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
- Concomitant or recent (within 14 days) treatment with an Concomitant treatment with monoamine oxidase inhibitors (MAOIs)
Adverse Reactions
Serious
- See Sympathomimetic toxicity
- Abuse potential
- Hypersensitivity reaction, angioedema, anaphylaxis
- Leukopenia, thrombocytopenia, anemia
- Psychosis, agitation
- CVA, ICH, vasculitis, seizure
- Serotonin syndrome
- Arrhythmia
- Hepatic injury
- Rhabdomyolysis
Common
- Decreased appetite, weight loss, poor weight gain/growth suppression
- Insomnia, anxiety/restlessness/agitation
- Headache, dizziness, tremor, dyskinesia
- Blurred vision
- Tachycardia, palpitations, chest pain
- Cough, nasopharyngitis
- Dry mouth, nausea/vomiting, abdominal pain, dyspepsia, abnormal LFTs
- Pruritus, urticaria, hyperhidrosis
- Arthralgia
Pharmacology
- Half-life: 2-4h
- Metabolism: Hepatic
- Excretion: Mostly renal
Mechanism of Action
- Norepinephrine and dopamine reuptake inhibitor