Difference between revisions of "Metal fume fever"

(Clinical Features)
(Clinical Features)
Line 9: Line 9:
*+/- [[SOB]], [[chest pain]], [[pneumonitis]]
*+/- [[SOB]], [[chest pain]], [[pneumonitis]]
**Rarely, severe lung injury, [[ARDS]] picture
**Rarely, severe lung injury, [[ARDS]] picture
*+/- [[hypotension]], [[AMS|LOC]], [[seizure]] in severe cases
*+/- [[hypotension]], [[AMS|LOC]], [[seizure]], [[AKI]] in severe cases
==Differential Diagnosis==
==Differential Diagnosis==

Latest revision as of 15:16, 27 August 2019


  • AKA brass founders' ague, brass shakes, zinc shakes, galvie flu, metal dust fever, Welding Shivers, Monday morning fever
  • Syndrome caused by inhalation of certain metals (most commonly zinc, copper, cadmium, but also aluminum, lead, nickel and various other metals[1]) in form of dust or fumes, usually through hot metalworking such as welding, brazing, smelting, or soldering.
  • Thought to be due to metals stimulating cytokine release

Clinical Features

Differential Diagnosis

Influenza-Like Illness


  • Clinical diagnosis, evaluate for alternate diagnoses
  • CXR and CT chest often unremarkable in milder cases but may show ground-glass opacities or other findings[2]
  • CBC- may have leukocytosis with neutrophil predominance[3]


  • Supportive
  • Most cases self-limiting within 24-48h


  • Discharge if clinically stable

See Also

External Links


  1. https://www.twi-global.com/technical-knowledge/faqs/faq-what-is-metal-fume-fever
  2. Kunimasa, Kei; Arita, Machiko; Tachibana, Hiromasa; Tsubouchi, Kazuya; Konishi, Satoshi; Korogi, Yohei; Nishiyama, Akihiro; Ishida, Tadashi (2011). "Chemical Pneumonitis and Acute Lung Injury Caused by Inhalation of Nickel Fumes". Internal Medicine. 50 (18): 2035–8.
  3. Kaye P, Young H, O'sullivan I. Metal fume fever: a case report and review of the literature. Emerg Med J. 2002;19(3):268-9.