Lymphoma: Difference between revisions
(Created page with "==Hodgkin Lymphoma== ===Background=== *Spreads from source lymph node to adjacent nodes *Bimodal distribution: young adulthood and older aged *Most common malignancy between ages...") |
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*Bimodal distribution: young adulthood and older aged | *Bimodal distribution: young adulthood and older aged | ||
*Most common malignancy between ages of 15-19 yo | *Most common malignancy between ages of 15-19 yo | ||
*Survival >90% in low-risk pts | |||
==Diagnosis== | ===Diagnosis=== | ||
*Painless, firm, lymph node (usually cervical or supraclavicular) | *Painless, firm, lymph node (usually cervical or supraclavicular) | ||
*"B" symptoms: fever, night sweats, wt loss | *"B" symptoms: fever, night sweats, wt loss | ||
==Work-Up== | ===Work-Up=== | ||
*CXR | *CXR | ||
*CT neck/C/A/P | *CT neck/C/A/P | ||
*LN biopsy | |||
==DDx== | ===DDx=== | ||
Cervical lymphadenopathy | |||
#Non-Hodgkin lymphoma | |||
#Mononucleosis | |||
#Toxoplasmosis | |||
#Branchial cleft lesions | |||
#Cat scratch disease | |||
#Mycobacterial adenitis | |||
===Treatment=== | |||
*Manage acute complications | |||
**Superior vena cava syndrome | |||
**Upper airway compression | |||
***Do NOT give steroids | |||
== | ==Non-Hodgkin Lymphoma== | ||
===Background=== | |||
*May originate in lymphatic system or any organ in the body | |||
*Occurs in children >5yr old | |||
*Risk factors | |||
**Immunosuppression (HIV, Crohn, chemo recipients) | |||
===Diagnosis=== | |||
*Lymphadenopathy | |||
*Hepatosplenomegaly | |||
*"B" symptoms | |||
*GI | |||
**Bleeding, intussusception, N/V | |||
== | ===Work-Up=== | ||
*CBC | |||
*Chemistry | |||
*Uric acid | |||
*LFT | |||
*CXR | |||
== | ===Complications=== | ||
*Superior vena cava syndrome | |||
*Pleural/pericardial effusions | |||
*Spinal cord compression | |||
==Source== | ==Source== | ||
Revision as of 22:49, 29 June 2011
Hodgkin Lymphoma
Background
- Spreads from source lymph node to adjacent nodes
- Bimodal distribution: young adulthood and older aged
- Most common malignancy between ages of 15-19 yo
- Survival >90% in low-risk pts
Diagnosis
- Painless, firm, lymph node (usually cervical or supraclavicular)
- "B" symptoms: fever, night sweats, wt loss
Work-Up
- CXR
- CT neck/C/A/P
- LN biopsy
DDx
Cervical lymphadenopathy
- Non-Hodgkin lymphoma
- Mononucleosis
- Toxoplasmosis
- Branchial cleft lesions
- Cat scratch disease
- Mycobacterial adenitis
Treatment
- Manage acute complications
- Superior vena cava syndrome
- Upper airway compression
- Do NOT give steroids
Non-Hodgkin Lymphoma
Background
- May originate in lymphatic system or any organ in the body
- Occurs in children >5yr old
- Risk factors
- Immunosuppression (HIV, Crohn, chemo recipients)
Diagnosis
- Lymphadenopathy
- Hepatosplenomegaly
- "B" symptoms
- GI
- Bleeding, intussusception, N/V
Work-Up
- CBC
- Chemistry
- Uric acid
- LFT
- CXR
Complications
- Superior vena cava syndrome
- Pleural/pericardial effusions
- Spinal cord compression
Source
Tintinalli