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This page is for adult patients. For pediatric patients, see: leukemia (peds)


  • Hematologic malignancy that typically originates in bone marrow and results in high number of abnormal leukocytes or blasts

Types of Leukemia

Myeloid and Lymphoid lineage

Clinical Features

  • Varies by type


Differential Diagnosis


Workup Consideration

  • CXR
  • CBC with peripheral smear
  • Tumor lysis syndrome labs: chem7, ca, mg, phos, uric acid, UA, LDH
  • DIC labs: LFTs, Coags, FDP, D-Dimer, Haptoglobin, Fibrinogen
  • ESR, CRP
  • Reticulocyte count in anemia
  • Get extra purple top for flow cytometry, especially before transfusion


  • Address any complications
  • Consult oncology for new diagnosis

See Also