Ketorolac: Difference between revisions
| Line 16: | Line 16: | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
*Lactation: Enters breast milk, use caution | *Lactation: Enters breast milk, use caution | ||
*Elderly (> 65 yo): Decrease dose by 50% | |||
*Renal Dosing | *Renal Dosing | ||
**Mild-Moderate impairment: Decrease dose by 50% | **Mild-Moderate impairment: Decrease dose by 50% | ||
Revision as of 01:10, 23 May 2015
General
- Type: NSAID
- Dosage Forms: 15 mg/mL, 30 mg/mL injection
- Common Trade Names: Toradol
Adult Dosing
- Acute pain:
- IM: 30-60 mg x 1 or 30 mg q6h
- IV: 30 mg x 1, then 15-30 mg q6h
- Black box warning against tx for > 5 days
Pediatric Dosing
- N/A
Special Populations
- Pregnancy Rating: C
- Lactation: Enters breast milk, use caution
- Elderly (> 65 yo): Decrease dose by 50%
- Renal Dosing
- Mild-Moderate impairment: Decrease dose by 50%
- Severe impairment or HD: Contraindicated
- Hepatic Dosing: No dose change, but may increase LFTs
Contraindications
- Allergy to class/drug
- Active or prior PUD, recent GIB
- Severe renal disease or HD
- Bleeding diathesis
Adverse Reactions
Serious
- Bleeding, MI, CVA, GI bleed/perforation, Hyperkalemia
Common
- Dispepsia, nausea, HA
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: