Intravenous drug use

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Background

  • Complications in the Intravenous drug using population spans all organ systems in addition to the Toxidromes related to used chemical.

Complications by System

Cardiovascular

Soft Tissue Infections

Pulmonary

  • PE
  • Talcosis (trash lung)
  • Pulmonary hypertension
  • Pneumothorax
    • from injecting in neck veins

Skeletal

Central Nervous System

  • Endocarditis
  • SAH
    • especially with sympathomimetics such as Meth and Cocaine
  • Brain abscess
  • Subdural empyema
  • Botulism
    • especially with skin popping of black tar heroine
  • CVA

Ocular

  • Fungal Endophthalmitis
  • Amaurosis Fugax

Hematogenous

Infectious Disease

  • Cotton fever
    • Occurs when cotton is used to filter drugs like heroin and due to the exotoxin from Pantoea agglomerans which colonizes cotton plants[2]
  • HIV related
  • TB


Sources

  1. http://www.harmreductionjournal.com/content/6/1/30
  2. D. W. Harrison et al."'Cotton Fever': a benign febrile syndrome in intravenous drug abusers", Journal of Emergency Medicine, March–April 1990, pp. 135-139