Infectious mononucleosis
Revision as of 21:48, 11 June 2012 by Rossdonaldson1 (talk | contribs)
Background
- Caused by Epstein-Barr virus
- CMV and HHV-6 may cause mononucleosis-like illnesses
Clinical Features
- Triad of:
- Fever
- Pharyngitis
- Lymphadenopathy
- Symptoms
- abrupt or insidious, ha, fever & malaise common w/ st & lad to follow
- rash in 10-15% usu btwn 4th-6th day of illness
- red macular or maculopapular morbilliform rash of trunk & upper arms
- occ involves face, thigh & legs, periorbital & eyelid edema in 50% of cases
Diagnosis
- Heterophile antibody (monospot) test
- Up to 25% of pts in 1st week of symptoms may have false negative test
- 10% of pts w/ EBV infection will be persistently negative
- Amoxicillin reaction
- Amoxicillin in pt w/ EBV will cause maculopapular rash in most
Treatment
- Supportive
Source
Tintinalli