Infectious mononucleosis: Difference between revisions
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*Amoxicillin reaction | *Amoxicillin reaction | ||
**Amoxicillin in pt w/ EBV will cause maculopapular rash in most | **Amoxicillin in pt w/ EBV will cause maculopapular rash in most | ||
*Definitive testing for suspected Mono during pregnancy (to r/o other pathology) | |||
**Send for: Epstein Barr virus, cytomegalovirus, and HIV | |||
==Treatment== | ==Treatment== |
Revision as of 16:47, 25 September 2012
Background
- Caused by Epstein-Barr virus
- CMV and HHV-6 may cause mononucleosis-like illnesses
Clinical Features
- Triad of:
- Fever
- Pharyngitis
- Lymphadenopathy
- Symptoms
- abrupt or insidious, ha, fever & malaise common w/ st & lad to follow
- Rash in 10-15% usu btwn 4th-6th day of illness
- red macular or maculopapular morbilliform rash of trunk & upper arms
- occ involves face, thigh & legs, periorbital & eyelid edema in 50% of cases
Diagnosis
- Heterophile antibody (monospot) test
- Up to 25% of pts in 1st week of symptoms may have false negative test
- 10% of pts w/ EBV infection will be persistently negative
- Amoxicillin reaction
- Amoxicillin in pt w/ EBV will cause maculopapular rash in most
- Definitive testing for suspected Mono during pregnancy (to r/o other pathology)
- Send for: Epstein Barr virus, cytomegalovirus, and HIV
Treatment
- Supportive
Source
Tintinalli