Ibutilide: Difference between revisions
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==General== | ==General== | ||
*Type: [[Antiarrhythmics]] | *Type: [[Antiarrhythmics]] | ||
*Dosage Forms: | *Dosage Forms:IV 1mg/10mL | ||
*Common Trade Names: | *Common Trade Names: Corvert | ||
==Adult Dosing== | ==Adult Dosing== | ||
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==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: Use in pregnancy may be considered, but data is sparse | ||
*[[Lactation risk categories|Lactation risk]]: | *[[Lactation risk categories|Lactation risk]]: Not recoemmended | ||
*Renal Dosing | *Renal Dosing: none | ||
*Hepatic Dosing: none | |||
*Hepatic Dosing | |||
==Indications == | ==Indications== | ||
*Rapid conversion of recent-onset A-fib/flutter to NSR | *Rapid conversion of recent-onset A-fib/flutter to NSR | ||
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*Mechanism of Action: Class III - Prolongs AP and refractory period | *Mechanism of Action: Class III - Prolongs AP and refractory period | ||
===Kinetics === | ===Kinetics=== | ||
*Onset of action = 20-30min | *Onset of action = 20-30min | ||
*Duration of action = 24hr | *Duration of action = 24hr | ||
Revision as of 20:33, 26 January 2019
General
- Type: Antiarrhythmics
- Dosage Forms:IV 1mg/10mL
- Common Trade Names: Corvert
Adult Dosing
- Loading dose = 1mg IV in 50mL D5W over 10min (wt>60kg)
- Loading dose = 0.01mg/kg IV in 50mL D5W over 10min (wt<60kg)
- Dose may be repeated 10min after completion of 1st dose
Pediatric Dosing
Special Populations
- Pregnancy Rating: Use in pregnancy may be considered, but data is sparse
- Lactation risk: Not recoemmended
- Renal Dosing: none
- Hepatic Dosing: none
Indications
- Rapid conversion of recent-onset A-fib/flutter to NSR
Contraindications
- Allergy to class/drug
Adverse Reactions
- QT prolongation, V-tach, torsades
- Observe for 4hr after infusion
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action: Class III - Prolongs AP and refractory period
Kinetics
- Onset of action = 20-30min
- Duration of action = 24hr