Human papillomavirus: Difference between revisions
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==Background== | ==Background== | ||
*Most common STI in US. | *Abbreviation: HPV | ||
*Associated with cervical, vulvar, penile, anal | *Most common [[STI]] in US. | ||
*Vaccine available for adolescents 11 and older, and immunocompromised patients | *Over 200 HPV types, with 40 that infect the genital mucosa <ref> Cdc.gov. (2018). Surveillance Manual | HPV | Vaccine Preventable Diseases | CDC. [online] Available at: https://www.cdc.gov/vaccines/pubs/surv-manual/chpt05-hpv.html [Accessed 3 May 2018]. </ref> | ||
*Associated with cervical, vulvar, penile, anal and oropharyngeal cancer. | |||
*Vaccine available for adolescents 11 and older, and immunocompromised patients. | |||
===HPV Types and Associated Disease Entities=== | |||
{| class="wikitable" style="margin:1em;" | |||
|- | |||
! Disease | |||
! HPV type | |||
|- | |||
| Common [[wart]]s | |||
| 2, 7, 22 | |||
|- | |||
| [[Plantar wart]]s | |||
| 1, 2, 4, 63 | |||
|- | |||
| Verruca plana (flat) | |||
| 3, 10, 28 | |||
|- | |||
| [[Condyloma acuminata]] (anogenital) | |||
| 6, 11, 42, 44 and others | |||
|- | |||
| Anal dysplasia (lesions) | |||
| 6, 16, 18, 31, 53, 58 | |||
|- | |||
| Genital cancers | |||
| | |||
*Highest risk: 16, 18, 31, 45 | |||
*Other high-risk: 33, 35, 39, 51, 52, 56, 58, 59 | |||
*Probably high-risk: 26, 53, 66, 68, 73, 82 | |||
|- | |||
| Epidermodysplasia verruciformis | |||
| more than 15 types | |||
|- | |||
| Focal epithelial hyperplasia (mouth) | |||
| 13, 32 | |||
|- | |||
| Mouth papillomas | |||
| 6, 7, 11, 16, 32 | |||
|- | |||
| Oropharyngeal cancer | |||
| 16 | |||
|- | |||
| Verrucous cyst | |||
| 60 | |||
|- | |||
| Laryngeal papillomatosis | |||
| 6, 11 | |||
|} | |||
==Clinical Features== | ==Clinical Features== | ||
[[File:Dornwarzen.jpg|thumb|Warts on toe.]] | |||
[[File:Largeplanterwart.jpg|thumb|Plantar wart on sole of foot.]] | |||
*Most infections asymptomatic | *Most infections asymptomatic | ||
*Anogenital warts (Condyloma acuminata) | *Anogenital warts ([[Condyloma acuminata]]) | ||
**painless flesh-colored papules or cauliflower-like projections | **painless flesh-colored papules or cauliflower-like projections | ||
**Contagious via skin contact | **Contagious via skin contact | ||
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==Differential Diagnosis== | ==Differential Diagnosis== | ||
{{STD DDX}} | |||
== | ==Evaluation== | ||
*Clinical | *Clinical diagnosis | ||
*Pap smear for cervical lesions | *Pap smear for cervical lesions | ||
==Management== | ==Management== | ||
*Safe-sex counseling | *Safe-sex counseling (HPV-2) | ||
==Disposition== | ==Disposition== | ||
Outpatient | *Outpatient follow up | ||
==See Also== | ==See Also== | ||
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==External Links== | ==External Links== | ||
*http://www.cdc.gov/std/hpv/stdfact-hpv.htm | |||
==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:ID]] | |||
[[Category:Dermatology]] | |||
[[Category:OBGYN]] | |||
[[Category:Urology]] |
Revision as of 19:38, 10 September 2020
Background
- Abbreviation: HPV
- Most common STI in US.
- Over 200 HPV types, with 40 that infect the genital mucosa [1]
- Associated with cervical, vulvar, penile, anal and oropharyngeal cancer.
- Vaccine available for adolescents 11 and older, and immunocompromised patients.
HPV Types and Associated Disease Entities
Disease | HPV type |
---|---|
Common warts | 2, 7, 22 |
Plantar warts | 1, 2, 4, 63 |
Verruca plana (flat) | 3, 10, 28 |
Condyloma acuminata (anogenital) | 6, 11, 42, 44 and others |
Anal dysplasia (lesions) | 6, 16, 18, 31, 53, 58 |
Genital cancers |
|
Epidermodysplasia verruciformis | more than 15 types |
Focal epithelial hyperplasia (mouth) | 13, 32 |
Mouth papillomas | 6, 7, 11, 16, 32 |
Oropharyngeal cancer | 16 |
Verrucous cyst | 60 |
Laryngeal papillomatosis | 6, 11 |
Clinical Features
- Most infections asymptomatic
- Anogenital warts (Condyloma acuminata)
- painless flesh-colored papules or cauliflower-like projections
- Contagious via skin contact
- Cervical cancer
Differential Diagnosis
Sexually transmitted diseases
- Chancroid
- Chlamydia trachomatis
- Granuloma inguinale
- Hepatitis B
- Herpes Simplex Virus-2
- HIV
- Human papillomavirus
- Lymphogranuloma venereum
- Neisseria gonorrhoeae
- Trichomonas
- Syphilis
Evaluation
- Clinical diagnosis
- Pap smear for cervical lesions
Management
- Safe-sex counseling (HPV-2)
Disposition
- Outpatient follow up
See Also
External Links
References
- ↑ Cdc.gov. (2018). Surveillance Manual | HPV | Vaccine Preventable Diseases | CDC. [online] Available at: https://www.cdc.gov/vaccines/pubs/surv-manual/chpt05-hpv.html [Accessed 3 May 2018].