Helicobacter pylori: Difference between revisions
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==Background== | ==Background== | ||
*''H. pylori'' is a gram negative bacteria that causes gastritis, peptic ulcer disease, and gastric adenocarcinoma. | |||
''H. pylori'' is a gram negative bacteria that causes gastritis, peptic ulcer disease, and gastric adenocarcinoma. | |||
==Clinical Features== | ==Clinical Features== | ||
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*[[Gastroesophageal Reflux Disease]] | *[[Gastroesophageal Reflux Disease]] | ||
==Differential Diagnosis== | |||
==Diagnosis== | ==Diagnosis== | ||
*Non-invasive Testing | *Non-invasive Testing | ||
**Urea Breath Testing | **Urea Breath Testing | ||
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==Management== | ==Management== | ||
*Triple Therapy | *Triple Therapy | ||
*PPI plus clarithromycin 500 mg twice daily, and amoxicillin 1000 mg twice daily for 10-14 days | **PPI plus clarithromycin 500 mg twice daily, and amoxicillin 1000 mg twice daily for 10-14 days | ||
*If PCN allergic: PPI plus clarithromycin 500 mg twice daily, metronidazole 500 mg twice daily for 10-14 days | **If PCN allergic: PPI plus clarithromycin 500 mg twice daily, metronidazole 500 mg twice daily for 10-14 days | ||
==Disposition== | ==Disposition== | ||
*Discharge with GI outpatient follow-up | |||
*Discharge with GI outpatient follow-up | |||
==See Also== | ==See Also== | ||
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==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:GI]] | |||
Revision as of 11:21, 17 November 2015
Background
- H. pylori is a gram negative bacteria that causes gastritis, peptic ulcer disease, and gastric adenocarcinoma.
Clinical Features
- Epigastric abdominal pain
- Gastroesophageal Reflux Disease
Differential Diagnosis
Diagnosis
- Non-invasive Testing
- Urea Breath Testing
- Serology - ELISA
- Stool Antigen Assay
- Invasive Testing - Endoscopy
Management
- Triple Therapy
- PPI plus clarithromycin 500 mg twice daily, and amoxicillin 1000 mg twice daily for 10-14 days
- If PCN allergic: PPI plus clarithromycin 500 mg twice daily, metronidazole 500 mg twice daily for 10-14 days
Disposition
- Discharge with GI outpatient follow-up