Flunitrazepam toxicity: Difference between revisions
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==Background== | ==Background== | ||
*Also known as Rohypnol | |||
*Used in Europe and Asia for Insomnia and Pre-op sedation | *Used in Europe and Asia for Insomnia and Pre-op sedation | ||
*Used in US as "date-rape" agent | *Used in US as "date-rape" agent | ||
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==Differential Diagnosis== | ==Differential Diagnosis== | ||
{{Sedatve/hypnotic toxicity types}} | |||
==Evaluation== | |||
==Management== | ==Management== | ||
==Disposition== | ==Disposition== | ||
==See Also== | ==See Also== | ||
*[[Benzodiazepines]] | |||
*[[Sedative/hypnotic toxicity]] | |||
==External Links== | ==External Links== | ||
==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:Toxicology]] |
Latest revision as of 06:34, 13 July 2017
Background
- Also known as Rohypnol
- Used in Europe and Asia for Insomnia and Pre-op sedation
- Used in US as "date-rape" agent
- An intermediate acting benzodiazepine
- Has strong affinity for benzodiazepine receptor
Clinical Features
- CNS depression within 30 minutes
- Patients can usually be aroused with noxious stimuli
- Half life 16-35 hours but coma can last 48h
Differential Diagnosis
Sedative/hypnotic toxicity
- Absinthe
- Barbiturates
- Benzodiazepines
- Chloral hydrate
- Gamma hydroxybutyrate (GHB)
- Baclofen toxicity
- Opioids
- Toxic alcohols
- Xylazine toxicity