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Background
Clinical Features
- Initially mild URI-type symptoms
- Malaise, myalgias, and headache 7-10 days prior to rash [1]
- "Slapped cheeks" rash
- Abrupt appearance on day 3-4
- Lasts 4-5 days
- Macular erythema develops on trunk/limbs 2 days after appearance of facial rash
- Distinctive aspect of rash: faces with central clearing, giving a reticulated or lacy appearance
- May last 1 week
- Rash may recur within 3 week period
- Papulopurpuric glove-and-sock syndrome
- Associated symptoms include fever, headache, sore throat, cough, coryza, nausea and vomiting
Differential Diagnosis
Evaluation
- Clinical diagnosis, based on history and physical exam
Management
Disposition
- Discharge most patients
- Referral to maternal-fetal medicine specialist for infection in pregnancy
- Admit if aplastic crisis
Complications
See Also
References
- ↑ Sara Bode; Contagious Exanthematous Diseases. Quick References 2022; 10.1542/aap.ppcqr.396150
- ↑ Shirk A, Sorrentino A. Viral Exanthems. In: Schafermeyer R, Tenenbein M, Macias CG, Sharieff GQ, Yamamoto LG. eds. Strange and Schafermeyer's Pediatric Emergency Medicine, 4e. New York, NY: McGraw-Hill; 2015