Difference between revisions of "Enoxaparin"

(Created page with "==Treatment== DOSE = 1mg/kg sq bid *No need to monitor PTT and adjust dosages. ==Uses/Benefits== - DVT/PE - equal efficacy - Unstable Angina (better than heparin) - Is...")
 
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==Treatment==
+
==General==
 +
*Type: [[Low molecular weight heparin]]
 +
*Dosage Forms:
 +
*Common Trade Names: Lovenox
  
 +
==Adult Dosing==
  
DOSE = 1mg/kg sq bid
+
==Pediatric Dosing==
  
*No need to monitor PTT and adjust dosages.
+
==Special Populations==
 +
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]:
 +
*Lactation:
 +
*Renal Dosing
 +
**Renal impairment (creatinine clearance <30)
 +
***Use 50% of usual dose or use UFH instead
 +
**Adult
 +
**Pediatric
 +
*Hepatic Dosing
 +
**Adult
 +
**Pediatric
 +
*Obesity
 +
**Weight-based dosing safe up to 190kg (no data available thereafter)
  
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==Indications==
 +
*[[DVT]]
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*[[PE]]
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*[[NSTEMI]]
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*[[STEMI]]
  
==Uses/Benefits==
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==Contraindications==
 +
*Allergy to class/drug
  
 +
==Adverse Reactions==
 +
*Bleeding
 +
*Pruritus
 +
*Local skin reaction
  
- DVT/PE - equal efficacy
+
==Pharmacology==
 
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*Half-life:
- Unstable Angina (better than heparin)
+
*Metabolism:
 
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*Excretion:
- Ischemic Stroke - (LMWH benefit at 6 months)
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*Mechanism of Action:
 
 
- Prevent prolonged hospitalization
 
 
 
- Rapid neutralization with protamine possible
 
 
 
1:1 mg upto 50 for lovenox in last 8hours
 
 
 
- Renal insufficiency (creatinine >2), liver disease, pregnancy, or obesity
 
 
 
 
 
 
==Source ==
 
 
 
 
 
7/2/09 PANI
 
 
 
  
 +
==See Also==
 +
*[[Heparin (Unfractionated)]]
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*[[Coagulopathy (Main)]]
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*[[Anticoagulant reversal for life-threatening bleeds]]
  
 +
==References==
 +
<references/>
  
 +
[[Category:Pharmacology]]
 
[[Category:Heme/Onc]]
 
[[Category:Heme/Onc]]

Latest revision as of 06:11, 11 August 2016

General

Adult Dosing

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Renal impairment (creatinine clearance <30)
      • Use 50% of usual dose or use UFH instead
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric
  • Obesity
    • Weight-based dosing safe up to 190kg (no data available thereafter)

Indications

Contraindications

  • Allergy to class/drug

Adverse Reactions

  • Bleeding
  • Pruritus
  • Local skin reaction

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

References