Difference between revisions of "Eczema herpeticum"

(References)
 
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*Treatment to cover [[Staph]] and [[Strep]]
 
*Treatment to cover [[Staph]] and [[Strep]]
 
*[[Bactrim]] 10mg/kg/d in 2 divided doses '''OR''' [[clindamycin]] 24mg/kg/d divided into 3 doses x10d
 
*[[Bactrim]] 10mg/kg/d in 2 divided doses '''OR''' [[clindamycin]] 24mg/kg/d divided into 3 doses x10d
*[[Acyclovir]] 80mg/kg/d in 3 divided doses x10
+
*[[Acyclovir]] 80mg/kg/d in 3 divided doses x10<ref>Aronson PL, Yan AC, Mittal MK, Mohamad Z, Shah SS. Delayed Acyclovir and Outcomes of Children Hospitalized With Eczema Herpeticum. Pediatrics. 2011;128(6):1161-1167. doi:10.1542/peds.2011-0948.</ref>
  
 
==Disposition==
 
==Disposition==
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==References==
 
==References==
 
<references/>
 
<references/>
*Aronson PL, Yan AC, Mittal MK, Mohamad Z, Shah SS. Delayed Acyclovir and Outcomes of Children Hospitalized With Eczema Herpeticum. Pediatrics. 2011;128(6):1161-1167. doi:10.1542/peds.2011-0948.
 
*Hinz T, Zaccaro D, Byron M, et al. ATOPIC DERMO-RESPIRAT'''OR'''Y SYNDROME IS A C'''OR'''RELATE OF ECZEMA HERPETICUM. Allergy. 2011;66(7):925-933. doi:10.1111/j.1398-9995.2010.02538.x.
 
  
 
[[Category:Dermatology]]
 
[[Category:Dermatology]]
 
[[Category:ID]]
 
[[Category:ID]]

Latest revision as of 22:13, 10 September 2020

Background

Clinical Features

Eczema Herpeticum in immunocompromised patient.[2]).
Eczema herpticum in child.[3]
  • Development of vesicular eruptions containing HSV 1 or 2 in areas of epidermis previously affected by atopic dermatitis
  • Lesions may appear similar to impetigo[4]
  • Fever is common
  • Multiple organ systems can become involved, resulting in lymphadenopathy, keratoconjunctivitis (potentially sight-threatening),meningitis, encephalitis, etc [5].
  • Lesions may become secondarily infected by bacteria, mainly with staph aureus[6].
  • The following is associated with increased susceptibility to Eczema Herpeticum[7]:
    • Early age of onset of eczema
    • History of food allergies or asthma[8]
    • Larger surface area of eczema
    • Eczema of the head/neck
    • Increased levels of IgE

Differential Diagnosis

Herpes Simplex Virus-1

Evaluation[9]

  • Clinical
  • Viral culture from swabs of wounds
  • Tzanck smears showing multi-nucleated giant cells
  • Direct Fluorescence antigen test for HSV

Management

Disposition

See Also

External Links

References

  1. Leung DYM. Why is eczema herpeticum unexpectedly rare? Antiviral research. 2013;98(2):153-157. doi:10.1016/j.antiviral.2013.02.010.
  2. Bagazgoitia L, Beà S, Garate M, Moreno R, Jaén P. ECZEMA HERPETICUM IN A PATIENT WITH TERMINAL RENAL FAILURE UNDER NARROW-BAND UVB THERAPY. Indian Journal of Dermatology. 2010;55(2):200-201. doi:10.4103/0019-5154.62744.
  3. Leung DYM. Why is eczema herpeticum unexpectedly rare? Antiviral research. 2013;98(2):153-157. doi:10.1016/j.antiviral.2013.02.010.
  4. Liaw F-Y, Huang C-F, Hsueh J-T, Chiang C-P. Eczema herpeticum: A medical emergency. Canadian Family Physician. 2012;58(12):1358-1361.
  5. Leung DYM. Why is eczema herpeticum unexpectedly rare? Antiviral research. 2013;98(2):153-157. doi:10.1016/j.antiviral.2013.02.010.
  6. Leung DYM. Why is eczema herpeticum unexpectedly rare? Antiviral research. 2013;98(2):153-157. doi:10.1016/j.antiviral.2013.02.010.
  7. Bagazgoitia L, Beà S, Garate M, Moreno R, Jaén P. ECZEMA HERPETICUM IN A PATIENT WITH TERMINAL RENAL FAILURE UNDER NARROW-BAND UVB THERAPY. Indian Journal of Dermatology. 2010;55(2):200-201. doi:10.4103/0019-5154.62744.
  8. Leung DYM. Why is eczema herpeticum unexpectedly rare? Antiviral research. 2013;98(2):153-157. doi:10.1016/j.antiviral.2013.02.010.
  9. Liaw F-Y, Huang C-F, Hsueh J-T, Chiang C-P. Eczema herpeticum: A medical emergency. Canadian Family Physician. 2012;58(12):1358-1361.
  10. Aronson PL, Yan AC, Mittal MK, Mohamad Z, Shah SS. Delayed Acyclovir and Outcomes of Children Hospitalized With Eczema Herpeticum. Pediatrics. 2011;128(6):1161-1167. doi:10.1542/peds.2011-0948.