EBQ:San Francisco Syncope Rule

Under Review Journal Club Article

Quinn J. et al.. "Prospective validation of the San Francisco Syncope Rule to predict patients with serious outcomes". Ann Emerg Med. 2006. 31(26):2992-6.
PubMed Full text PDF

Clinical Question

Can the San Francisco Syncope Rule be used in clinical practice to risk stratify patients presenting with syncope?

Major Points

Criteria (CHESS Pneumonic)

• CHF History
• Hct < 30%
• ECG Abnormality
• SOB history
• SBP < 90mmHg at triage

Study Design

• A prospective cohort study
• Consecutive patients with syncope or near syncope presenting to an emergency department of a large, urban teaching hospital were identified and enrolled from July 15, 2002 to August 31, 2004
• Physicians prospectively applied the San Francisco Syncope Rule
  • Patient follow up performed to determine if the patient suffered a predefined serious outcome within 30 days of their ED visit
  • Physicians completed a short Web-based form and enrolled patients after their assessment
• Study investigators reviewed all data forms in order to ensure the correct interpretation of the rule,

Population

Patient Demographics

• 364 men, 427 females
• Mean age: 61
• Admitted: 469
• Patients with serious outcomes after ED visit: 54 (6.8%)
  • Death: 3
  • Arrhythmia: 23
  • Myocardial Infarction: 11
  • Valvular Heart Disease: 1
  • Significant Hemorrhage: 7
  • TIA/Stroke: 3
  • Sepsis: 3
  • Admission after ED Discharge : 3