EBQ:NIPPV in COPD
Under Review Journal Club Article
Brochard L et al. "Noninvasive ventilation for acute exacerbations of chronic obstructive pulmonary disease.". NEJM. 1995. 333(13):817-22.
PubMed Full text PDF
PubMed Full text PDF
Clinical Question
Can NIPPV be used to avoid endotracheal intubation in acute COPD exacerbation?
Conclusion
NIPPV could avoid endotracheal intubation, the length of the hospital stay, and the in-hospital mortality rate in the selected patients.
Major Points
Guidelines
Design
Multicenter prospective randomized trial at five hospitals