Disseminated intravascular coagulation: Difference between revisions
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==Background== | |||
#Distinguishing the coagulopathy of severe liver disease from DIC is difficult | |||
Abnormal laboratory values, including decreased platelets, decreased coagulation factors, and hypofibrinogenemia can be present in both conditions. However, the D-dimer assay should be normal or only minimally elevated from liver disease alone. | |||
==Causes== | ==Causes== | ||
#infection | #infection | ||
Revision as of 09:33, 12 October 2011
Background
- Distinguishing the coagulopathy of severe liver disease from DIC is difficult
Abnormal laboratory values, including decreased platelets, decreased coagulation factors, and hypofibrinogenemia can be present in both conditions. However, the D-dimer assay should be normal or only minimally elevated from liver disease alone.
Causes
- infection
- carcinoma
- acute leukemia
- trauma (head)
- shock
- liver disease
- pregnancy
- vascular disease
- envenomation
- ARDS
- transfusion reaction
Diagnosis
- PT high
- PTT high
- Platlet low
- Fibrinogen low
- FDP high
- D-dimer high
- RBCs fragmented
Treatment
See Heme: Bleeding Treatment
Source
1/26/06 DONALDSON (addapted from Tintinalli)