Diltiazem: Difference between revisions
Neil.m.young (talk | contribs) (Text replacement - "Rxn" to "Reactions") |
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== Adult Dosing == | ==Adult Dosing == | ||
*Loading dose = 0.25mg/kg (max=20mg) IV bolus over 2min | *Loading dose = 0.25mg/kg (max=20mg) IV bolus over 2min | ||
**If ineffective after 15min: 0.35mg/kg (max=25mg) over 2min | **If ineffective after 15min: 0.35mg/kg (max=25mg) over 2min | ||
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*See [[critical care quick reference]] for drug doses by weight | *See [[critical care quick reference]] for drug doses by weight | ||
== Contraindications == | ==Contraindications == | ||
*Wide-complex tachycardia due to bypass tract | *Wide-complex tachycardia due to bypass tract | ||
== Indications == | ==Indications == | ||
*Conversion of PSVT to NSR | *Conversion of PSVT to NSR | ||
*Slow RVR in a-fib/flutter | *Slow RVR in a-fib/flutter | ||
== Mechanism of Action == | ==Mechanism of Action == | ||
*Class IV - Inhibits Ca influx | *Class IV - Inhibits Ca influx | ||
**Slows AV nodal conduction | **Slows AV nodal conduction | ||
== Adverse Drug Reactionss == | ==Adverse Drug Reactionss == | ||
Bradycardia, CHF, AV block, BBB, hypotension | Bradycardia, CHF, AV block, BBB, hypotension | ||
== Kinetics == | ==Kinetics == | ||
*Onset of action = 2-3min (IV) | *Onset of action = 2-3min (IV) | ||
*Duration of action = 1-3hr (IV) | *Duration of action = 1-3hr (IV) | ||
Revision as of 09:15, 5 July 2016
Adult Dosing
- Loading dose = 0.25mg/kg (max=20mg) IV bolus over 2min
- If ineffective after 15min: 0.35mg/kg (max=25mg) over 2min
- If effective: Start infusion at 5-15mg/hr
Pediatric Dosing
- See critical care quick reference for drug doses by weight
Contraindications
- Wide-complex tachycardia due to bypass tract
Indications
- Conversion of PSVT to NSR
- Slow RVR in a-fib/flutter
Mechanism of Action
- Class IV - Inhibits Ca influx
- Slows AV nodal conduction
Adverse Drug Reactionss
Bradycardia, CHF, AV block, BBB, hypotension
Kinetics
- Onset of action = 2-3min (IV)
- Duration of action = 1-3hr (IV)