Dementia with Lewy bodies

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Background

  • Neurodegenerative disorder (dementia)
  • More rapid progression than Alzheimer's or Parkinson's

Clinical Features

  • fluctuating cognition
  • recurrent visual hallucinations
  • Parkinsonian motor symptoms (cogwheel rigidity, shuffling gait, retropulsion)
  • REM-sleep disturbance
  • Neuroleptic sensitivity, increased risk for neuroleptic malignant syndrome
    • Acute worsening of cognition or delirium, with antipsychotics, benzodiazepines, anticholinergics, surgical anesthetics

Differential Diagnosis

Evaluation

Management

  • Avoid neuroleptics and anticholinergics
  • Supportive care, symptom management

Disposition

See Also

External Links

References