Delirium

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Background

Delirium vs. dementia vs. psych

Clinical Features

  • Main cognitive impairment is that of inattention (vs memory in dementia)
  • Generally develops over hours to days
  • Symptoms are classically described as fluctuating throughout the day (ie may appear normal in between episodes)

ED Confusion Assessment Method[1]

  • Acute onset of mental status changes and/or fluctuating course
  • Anattention
  • Disorganized thinking
  • Altered level of consciousness

A patient must possess both features 1 and 2 AND either 3 or 4 to meet delirium criteria

Differential Diagnosis

General Psychiatric

Diagnosis

Main goal is to find the underlying cause.

  • CBC (eg elevated WBC)
  • U/E/Cr (eg electrolyte derangements)
  • LFTs (eg hepatobiliary infection)
  • Urine analysis (eg UTI)
  • CXR (eg pneumonia)
  • ?Utox
  • ?CT/LP

Treatment

  • Treat underlying cause
  • Antipsychotics (eg haloperidol, risperidone) may be useful for hyperactive delirium with psychotic features

Disposition

  • Admission

See Also

References

  1. Inouye SK, van Dyck CH, Alessi CA, et al. Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med 1990; 113:941.