Coagulopathy (main)

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Background

  • Primary hemostasis: damage to endothelial basement membrane and formation of platelet plug
  • Secondary hemostasis: coagulation cascade
Coagulation cascade

Clinical Features

  • Spontaneous bleeding
  • Bleeding out of proportion
  • Swollen joints
  • Epistaxis
  • Bleeding gums
  • Menometrorrhagia
  • Easy bruising/petechiae
  • Hematuria

Differential Diagnosis

Coagulopathy

Platelet Related

Factor Related

Increased Clotting

Managment

See Also

References