Difference between revisions of "Coagulopathy (main)"

 
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==DDX==
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==Background==
*[[Vitamin K Deficiency]]
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*Primary hemostasis: damage to endothelial basement membrane and formation of platelet plug
*[[Warfarin (Coumadin)]]
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*Secondary hemostasis: coagulation cascade
*[[Heparin]]
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[[File:Coagulation cascade.png|thumbnail|Coagulation cascade]]
*[[Lovenox]]
 
*[[DIC]]
 
*[[Hemophilia]]
 
*[[Factor VIII Inhibitor]]
 
*[[Lupus Anticoagulan]]t]]
 
*[[Liver Disease Induced Coagulopathy]]
 
*[[Renal Disease Induced Coagulopathy]]
 
  
==Managment==
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==Clinical Features==
 +
*Spontaneous [[hemorrhage|bleeding]]
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*Bleeding out of proportion
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*Swollen joints
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*[[Epistaxis]]
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*Bleeding gums
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*[[vaginal Bleed Non-Pregnant|Menometrorrhagia]]
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*Easy bruising/[[petechiae]]
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*[[Hematuria]]
 +
 
 +
==Differential Diagnosis==
 +
{{Increased bleeding DDX}}
 +
 
 +
===Increased Clotting===
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*[[Disseminated Intravascular Coagulation (DIC)]]
 +
 
 +
==Management==
 
*[[Bleeding Treatments]]
 
*[[Bleeding Treatments]]
*[[Procedures in Patients with Coagulopathies]]
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*[[Procedures in patients with coagulopathies]]
*[[Warfarin (Coumadin) Reversal]]
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*[[Anticoagulant reversal]] (known medications)
*[[Dabigatran (Pradaxa) Reversal]]
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**[[Warfarin (Coumadin) Reversal]]
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**[[Dabigatran (Pradaxa) Reversal]]
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**[[Rivaroxaban reversal]]
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**[[Unfractionated heparin reversal]]
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*[[Anti-platelet agent reversal]]
  
 
==See Also==
 
==See Also==
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*[[Transfusions]]
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*[[Idarucizumab]]
  
==Source==
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==References==
*Tintinalli
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<references/>
*UpToDate
 
 
 
 
[[Category:Heme/Onc]]
 
[[Category:Heme/Onc]]

Latest revision as of 00:16, 1 October 2019

Background

  • Primary hemostasis: damage to endothelial basement membrane and formation of platelet plug
  • Secondary hemostasis: coagulation cascade
Coagulation cascade

Clinical Features

Differential Diagnosis

Coagulopathy

Platelet Related

Factor Related

Increased Clotting

Management

See Also

References