Chlorhexidine
Administration
- Type: Antiseptic
- Dosage Forms: Liquid, powder
- Routes of Administration: Topical
- Common Trade Names: Betasept, Chlorostat
- Commonly used for skin disinfection
- Antimicrobial activity lasts up to six hours
Adult Dosing
Pediatric Dosing
Special Populations
Pregnancy Rating
Lactation risk
Renal Dosing
- Adult:
- Pediatric:
Hepatic Dosing
- Adult:
- Pediatric:
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
Mechanism of Action
- Chlorhexidine cation binds to negatively charged bacterial cell wall
- Bacteriostatic at low concentrations, bacteriocidal at high concentrations
Comments
- CLABSI risk lowest when chlorhexidine allowed to dry for two minutes after application prior to placing central line