Cephalosporins

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1st Generation

2nd Generation

    • Intestinal anaerobes (why is agent of choice for colorectal sx)
    • Largely displaced by 3rd gen agents

3rd Generation

    • Drug of choice for serious infections due to:
      • Klebsiella
      • Enterobacter
      • Proteus
      • Haemophilus
    • Gonorrhea
    • Lyme Disease
    • Meningitis (+ vanc and ampicillin)
    • Pseudomonas meningitis (+ AG)

4th Generation

    • Resistant, nosocomial infections

See Also

Source

Goodman & Gilman's Pharmacology