Cephalosporins

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1st Generation

  • Skin and soft tissue infections (why is agent of choice before generalized symptoms)
  • Cross-reactivity of PCN allergy <10%

2nd Generation

  • Intestinal anaerobes (why is agent of choice for colorectal sx)
  • Largely displaced by 3rd gen agents

3rd Generation

4th Generation

  • Resistant, nosocomial infections

See Also

References

Goodman & Gilman's Pharmacology