Cephalosporins: Difference between revisions
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==1st Generation== | ==1st Generation== | ||
* Skin and soft tissue infections (why is agent of choice before gen sx) | *Skin and soft tissue infections (why is agent of choice before gen sx) | ||
* [[Ceftriaxone_Cross-reactivity|Cross-reactivity of PCN]] allergy <10% | *[[Ceftriaxone_Cross-reactivity|Cross-reactivity of PCN]] allergy <10% | ||
==2nd Generation== | ==2nd Generation== | ||
* Intestinal [[anaerobes]] (why is agent of choice for colorectal sx) | *Intestinal [[anaerobes]] (why is agent of choice for colorectal sx) | ||
* Largely displaced by 3rd gen agents | *Largely displaced by 3rd gen agents | ||
==3rd Generation== | ==3rd Generation== | ||
* Drug of choice for serious infections due to: | *Drug of choice for serious infections due to: | ||
** Klebsiella | **Klebsiella | ||
** Enterobacter | **Enterobacter | ||
** Proteus | **Proteus | ||
** Haemophilus | **Haemophilus | ||
* [[Gonorrhea]] | *[[Gonorrhea]] | ||
* [[Lyme Disease]] | *[[Lyme Disease]] | ||
* [[Meningitis]] (+ [[vanc]] and [[ampicillin]]) | *[[Meningitis]] (+ [[vanc]] and [[ampicillin]]) | ||
* Pseudomonas meningitis (+ AG) | *Pseudomonas meningitis (+ AG) | ||
==4th Generation== | ==4th Generation== | ||
* Resistant, nosocomial infections | *Resistant, nosocomial infections | ||
{{Template:Clinically Utilized Antibiotics}} | {{Template:Clinically Utilized Antibiotics}} |
Revision as of 17:25, 4 July 2016
1st Generation
- Skin and soft tissue infections (why is agent of choice before gen sx)
- Cross-reactivity of PCN allergy <10%
2nd Generation
- Intestinal anaerobes (why is agent of choice for colorectal sx)
- Largely displaced by 3rd gen agents
3rd Generation
- Drug of choice for serious infections due to:
- Klebsiella
- Enterobacter
- Proteus
- Haemophilus
- Gonorrhea
- Lyme Disease
- Meningitis (+ vanc and ampicillin)
- Pseudomonas meningitis (+ AG)
4th Generation
- Resistant, nosocomial infections
|
See Also
References
Goodman & Gilman's Pharmacology