Cephalosporins: Difference between revisions

Revision as of 07:30, 27 June 2017

1st Generation

Skin and soft tissue infections (why is agent of choice before generalized symptoms)
Cross-reactivity of PCN allergy <10%

2nd Generation

Intestinal anaerobes (why is agent of choice for colorectal sx)
Largely displaced by 3rd gen agents

3rd Generation

Drug of choice for serious infections due to:
- Klebsiella
- Enterobacter
- Proteus
- Haemophilus
Gonorrhea
Lyme Disease
Meningitis (+ vanc and ampicillin)
Pseudomonas meningitis (+ AG)

4th Generation

Resistant, nosocomial infections

References

Goodman & Gilman's Pharmacology

Authors:

@@ Line 1: / Line 1: @@
-*'''1st Gen [[Cephalosporins]]'''
+==1st Generation==
-** Cefazolin, [[Cephalexin]]
+*Skin and soft tissue infections (why is agent of choice before generalized symptoms)
-*** Skin and soft tissue infections (why is agent of choice before gen sx)
+*[[EBQ:Cephalosporin Cross-reactivity|Cross-reactivity of PCN]] allergy <10%
-** [[Ceftriaxone_Cross-reactivity|Cross-reactivity of PCN]] allergy <10%
-*'''2nd Gen Cephalosporins'''
+==2nd Generation==
-** Cefuroxime
+*Intestinal [[anaerobes]] (why is agent of choice for colorectal sx)
-*** Intestinal anaerobes (why is agent of chioce for colorectal sx)
+*Largely displaced by 3rd gen agents
-*** Largely displaced by 3rd gen agents
-*'''3rd Gen Cephalosporins'''
+==3rd Generation==
-** Ceftriaxone, Ceftazidime, Cefixime
+*Drug of choice for serious infections due to:
-*** Drug of choice for serious infections due to:
+**Klebsiella
-**** Klebsiella
+**Enterobacter
-**** Enterobacter
+**Proteus
-**** Proteus
+**Haemophilus
-**** Haemophilus
+*[[Gonorrhea]]
-*** Gonorrhea
+*[[Lyme Disease]]
-*** Lyme disease
+*[[Meningitis]] (+ [[vanc]] and [[ampicillin]])
-*** Meningitis (+ vanc and ampicillin)
+*Pseudomonas meningitis (+ AG)
-*** Pseudomonas meningitis (+ AG)
-*'''4th Gen Cephalosporins'''
+==4th Generation==
-** Cefepime
+*Resistant, nosocomial infections
-*** Resistant, nosocomial infections
-* Carbapenems
-** Imipenem (+ cilastatin), meropenem
-*** Cephalosporin-resistant nosocomial bacteria
-*** Empirical treatment of serious infections in patients who recently received other b-lactams
-* Aztreonam
-** Antimicrobial activity more closely resembles AG's (only active against gram -)
-*** Enterobacter, pseudomonas, H. influenzae, gonococci
-*** Little allergic cross-reactivity with B-lactam antibiotics
 {{Template:Clinically Utilized Antibiotics}}
@@ Line 34: / Line 25: @@
 ==See Also==
 *[[Antibiotics (Main)]]
+*[[Cephalosporin Cross-reactivity]]
-==Source==
+==References==
+<references/>
 Goodman & Gilman's Pharmacology
-[[Category:Drugs]]
+[[Category:Pharmacology]]
 [[Category:ID]]