Cardiac enzymes

Types

Cardiac Enzymes Over Time

Type	Interval (hours)	Peak Elevation (hours)	Return to Normal
Myoglobin	1-4	6-7	18-24 hours
Troponin I	3-12	10-24	3-10 days
Troponin T	3-12	10-24	5-14 days
CK-MB	4-12	12-24	2-3 days
LDH	8-12	24-48	10-14 days

Creatine Phosphokinase

• can be elevated in trauma, rhabdomyolysis, hyperthermia, physical activity, renal or endocrine disease, systemic infections
• if patient small with small muscle mass to begin with, total ck may not be elevated- so better to use CK index- is ratio of CKMB/ total CK. Elevated if > 3- 5%.
• CK Mass: with monoclonal antibody techniques, can directly measure ck mb mass as mmcg/L. More sensitive for detection of ami

See Also

• Troponin
• Acute Coronary Syndrome (Main)