Difference between revisions of "Captopril"

(Text replacement - "*Hyperkalemia" to "*Hyperkalemia")
 
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==Administration==
 
==Administration==
 
*Type: [[ACE inhibitor]]
 
*Type: [[ACE inhibitor]]
*Dosage Forms:
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*Dosage Forms: tablet
*Routes of Administration: Oral
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*Dosage Strengths: 12.5, 25, 50, 100mg
*Common Trade Names:
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*Routes of Administration: PO
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*Common Trade Names: Capoten, Captoril
  
 
==Adult Dosing==
 
==Adult Dosing==
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==Pharmacology==
 
==Pharmacology==
 
*Half-life: < 3 hours
 
*Half-life: < 3 hours
*Metabolism:  
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*Metabolism: Hepatic
 
*Excretion: Renal, dialzable
 
*Excretion: Renal, dialzable
  
 
==Mechanism of Action==
 
==Mechanism of Action==
*Inhibits angiotensin I-converting enzyme, blocks conversion of angiotensin I--> angiotensin II
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*Inhibits angiotensin I-converting enzyme, blocks conversion of angiotensin I→ angiotensin II
 
==Comments==
 
==Comments==
  
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==References==
 
==References==
 
<references/>
 
<references/>
[[Category:Pharmacology]]
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[[Category:Pharmacology]] [[Category:Cardiology]]

Latest revision as of 21:43, 19 September 2019

Administration

  • Type: ACE inhibitor
  • Dosage Forms: tablet
  • Dosage Strengths: 12.5, 25, 50, 100mg
  • Routes of Administration: PO
  • Common Trade Names: Capoten, Captoril

Adult Dosing

  • 6.25-150mg PO three times per day

Pediatric Dosing

Safety/efficacy not established in pediatric patients

Special Populations

Contraindications

  • Allergy to class/drug
  • History of ACE-inhibitor induced angioedema

Adverse Reactions

Serious

  • Angioedema
  • Stevens-Johnson syndrome
  • Agranulocytosis, neutropenia

Common

Pharmacology

  • Half-life: < 3 hours
  • Metabolism: Hepatic
  • Excretion: Renal, dialzable

Mechanism of Action

  • Inhibits angiotensin I-converting enzyme, blocks conversion of angiotensin I→ angiotensin II

Comments

See Also

References