Difference between revisions of "Calcium channel blockers"

(Text replacement - "== " to "==")
 
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{| class="wikitable"
+
{| {{table}}
 +
| align="center" style="background:#f0f0f0;"|'''Ca Blocker'''
 +
| align="center" style="background:#f0f0f0;"|'''BP/SVR'''
 +
| align="center" style="background:#f0f0f0;"|'''HR'''
 +
| align="center" style="background:#f0f0f0;"|'''SA/AV'''
 +
| align="center" style="background:#f0f0f0;"|'''CF'''
 +
| align="center" style="background:#f0f0f0;"|'''ION'''
 
|-
 
|-
| '''Ca Blocker'''
+
| [[Nifedipine]]||+++||+||-||+||-
| '''BP/SVR'''
 
| '''HR'''
 
| '''SA/AV'''
 
| '''CF'''
 
| '''ION'''
 
 
|-
 
|-
| [[Nifedipine]]
+
| [[Diltiazem]]||++||-||+||+||-
| +++
 
| +
 
| -
 
| +
 
| -
 
 
|-
 
|-
| [[Diltiazem]]
+
| [[Verapamil]]||+||--||++||+||-
| ++
 
| -
 
| +
 
| +
 
| -
 
 
|-
 
|-
| [[Verapamil]]
+
| [[Bepiridil]]||+++||(-)||min.||+++||-
| ++
 
| --
 
| ++
 
| +
 
| -
 
 
|-
 
|-
| [[Bepiridil]]
+
| [[Amlodipine]]||+++||+||+||||
| +
 
| (-)
 
| min.
 
| +++
 
| -
 
 
|-
 
|-
| [[Amlodipine]]
+
| [[Felodipine]]||||+||+||||
| +++
 
| +
 
| +
 
|  
 
|  
 
 
|-
 
|-
| [[Felodipine]]
+
| [[Nicardipine]]||||||||||
| +++
 
| +
 
| +
 
|  
 
|  
 
 
|-
 
|-
| [[Nicardipine]]
+
| [[Clevidipine]]||||||||||
|  
 
|  
 
|  
 
|  
 
|  
 
 
|}
 
|}
  
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*[[Diltiazem]]
 
*[[Diltiazem]]
 
**60-120 TID (CD: 180-360 qD)
 
**60-120 TID (CD: 180-360 qD)
*[[Verapamil]]: 80- 120 TID
+
*[[Verapamil]]: 80- 120mg TID
*[[Bepiridil]]: 200-400 QD
+
*[[Bepiridil]]: 200-400mg QD
*[[Amlodipine]]: 2.5- 20 (10) qD
+
*[[Amlodipine]]: 2.5- 20mg (10) qD
 
*[[Nicardipine]]
 
*[[Nicardipine]]
 +
**PO: 20-40mg q8hr, or 30-60mg (extended release) q12hr
 +
**IV: 5mg/hr by slow infusion (50ml/hr), titrate to maximum of 30mg/hr, then maintenance of 2.0 - 15.5mg/hr
 +
*[[Clevidipine]]: 1-2 mg IV per hour
  
 
==See Also==
 
==See Also==

Latest revision as of 17:38, 20 September 2019

Ca Blocker BP/SVR HR SA/AV CF ION
Nifedipine +++ + - + -
Diltiazem ++ - + + -
Verapamil + -- ++ + -
Bepiridil +++ (-) min. +++ -
Amlodipine +++ + +
Felodipine + +
Nicardipine
Clevidipine

CF = coronary flow, ION = ionotropy, SA/AV = nodes

Doses:

  • Nifedipine
    • 10-30 tid (Adalat CC: 30-90 qD)
  • Diltiazem
    • 60-120 TID (CD: 180-360 qD)
  • Verapamil: 80- 120mg TID
  • Bepiridil: 200-400mg QD
  • Amlodipine: 2.5- 20mg (10) qD
  • Nicardipine
    • PO: 20-40mg q8hr, or 30-60mg (extended release) q12hr
    • IV: 5mg/hr by slow infusion (50ml/hr), titrate to maximum of 30mg/hr, then maintenance of 2.0 - 15.5mg/hr
  • Clevidipine: 1-2 mg IV per hour

See Also