Difference between revisions of "Calcium channel blockers"

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Ca Blocker BP/SVR HR SA/AV CF ION
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{| {{table}}
Nifedipine +++ + - + -
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| align="center" style="background:#f0f0f0;"|'''Ca Blocker'''
Diltiazem ++ - + + -
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| align="center" style="background:#f0f0f0;"|'''BP/SVR'''
Verapamil ++ -- ++ + -
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| align="center" style="background:#f0f0f0;"|'''HR'''
Bepiridil + (-) min. +++ -
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| align="center" style="background:#f0f0f0;"|'''SA/AV'''
Amlodipine +++ + +
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| align="center" style="background:#f0f0f0;"|'''CF'''
Felodipine +++ + +
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| align="center" style="background:#f0f0f0;"|'''ION'''
CF = coronary flow, ION = ionotropy, SA/AV = nodes
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|-
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| [[Nifedipine]]||+++||+||-||+||-
 +
|-
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| [[Diltiazem]]||++||-||+||+||-
 +
|-
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| [[Verapamil]]||+||--||++||+||-
 +
|-
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| [[Bepiridil]]||+++||(-)||min.||+++||-
 +
|-
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| [[Amlodipine]]||+++||+||+||||
 +
|-
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| [[Felodipine]]||||+||+||||
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|-
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| [[Nicardipine]]||||||||||
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|-
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| [[Clevidipine]]||||||||||
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|}
  
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''CF = coronary flow, ION = ionotropy, SA/AV = nodes''
  
 
==Doses:==
 
==Doses:==
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*[[Nifedipine]]
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**10-30mg tid (Adalat CC: 30-90mg qD)
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*[[Diltiazem]]
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**60-120 TID (CD: 180-360mg qD)
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*[[Verapamil]]: 80- 120mg TID
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*[[Bepiridil]]: 200-400mg QD
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*[[Amlodipine]]: 2.5- 20mg (10) qD
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*[[Nicardipine]]
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**PO: 20-40mg q8hr, or 30-60mg (extended release) q12hr
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**IV: 5mg/hr by slow infusion (50ml/hr), titrate to maximum of 30mg/hr, then maintenance of 2.0 - 15.5mg/hr
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*[[Clevidipine]]: 1-2 mg IV per hour
  
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==See Also==
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*[[Calcium Channel Blocker Toxicity]]
  
Nif-10-30 tid (Adalat CC: 30-90 qD)
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[[Category:Cardiology]]
 
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[[Category:Pharmacology]]
Dilt.: 60-120 TID ( CD: 180-360 qD)
 
 
 
Verapamil: 80- 120 TID
 
 
 
Bepiridil: 200-400 QD
 
 
 
Amlodipine: 2.5- 20 (10) qD
 
 
 
 
 
 
 
 
 
[[Category:Cards]]
 

Latest revision as of 03:53, 6 March 2021

Ca Blocker BP/SVR HR SA/AV CF ION
Nifedipine +++ + - + -
Diltiazem ++ - + + -
Verapamil + -- ++ + -
Bepiridil +++ (-) min. +++ -
Amlodipine +++ + +
Felodipine + +
Nicardipine
Clevidipine

CF = coronary flow, ION = ionotropy, SA/AV = nodes

Doses:

  • Nifedipine
    • 10-30mg tid (Adalat CC: 30-90mg qD)
  • Diltiazem
    • 60-120 TID (CD: 180-360mg qD)
  • Verapamil: 80- 120mg TID
  • Bepiridil: 200-400mg QD
  • Amlodipine: 2.5- 20mg (10) qD
  • Nicardipine
    • PO: 20-40mg q8hr, or 30-60mg (extended release) q12hr
    • IV: 5mg/hr by slow infusion (50ml/hr), titrate to maximum of 30mg/hr, then maintenance of 2.0 - 15.5mg/hr
  • Clevidipine: 1-2 mg IV per hour

See Also