Difference between revisions of "Calcium channel blockers"

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{| border="1"
+
{| {{table}}
 +
| align="center" style="background:#f0f0f0;"|'''Ca Blocker'''
 +
| align="center" style="background:#f0f0f0;"|'''BP/SVR'''
 +
| align="center" style="background:#f0f0f0;"|'''HR'''
 +
| align="center" style="background:#f0f0f0;"|'''SA/AV'''
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| align="center" style="background:#f0f0f0;"|'''CF'''
 +
| align="center" style="background:#f0f0f0;"|'''ION'''
 
|-
 
|-
| '''Ca Blocker'''
+
| [[Nifedipine]]||+++||+||-||+||-
| '''BP/SVR'''
 
| '''HR'''
 
| '''SA/AV'''
 
| '''CF'''
 
| '''ION'''
 
 
|-
 
|-
| Nifedipine
+
| [[Diltiazem]]||++||-||+||+||-
| +++
 
| +
 
| -
 
| +
 
| -
 
 
|-
 
|-
| Diltiazem
+
| [[Verapamil]]||+||--||++||+||-
| ++
 
| -
 
| +
 
| +
 
| -
 
 
|-
 
|-
| Verapamil
+
| [[Bepiridil]]||+++||(-)||min.||+++||-
| ++
 
| --
 
| ++
 
| +
 
| -
 
 
|-
 
|-
| Bepiridil
+
| [[Amlodipine]]||+++||+||+||||
| +
 
| (-)
 
| min.
 
| +++
 
| -
 
 
|-
 
|-
| Amlodipine
+
| [[Felodipine]]||||+||+||||
| +++
 
| +
 
| +
 
| <br/>
 
| <br/>
 
 
|-
 
|-
| Felodipine
+
| [[Nicardipine]]||||||||||
| +++
+
|-
| +
+
| [[Clevidipine]]||||||||||
| +
 
| <br/>
 
| <br/>
 
 
|}
 
|}
  
 
''CF = coronary flow, ION = ionotropy, SA/AV = nodes''
 
''CF = coronary flow, ION = ionotropy, SA/AV = nodes''
  
== Doses: ==
+
==Doses:==
Nif-10-30 tid (Adalat CC: 30-90 qD)
+
*[[Nifedipine]]
 
+
**10-30mg tid (Adalat CC: 30-90mg qD)
Dilt.: 60-120 TID ( CD: 180-360 qD)
+
*[[Diltiazem]]
 
+
**60-120 TID (CD: 180-360mg qD)
Verapamil: 80- 120 TID
+
*[[Verapamil]]: 80- 120mg TID
 
+
*[[Bepiridil]]: 200-400mg QD
Bepiridil: 200-400 QD
+
*[[Amlodipine]]: 2.5- 20mg (10) qD
 +
*[[Nicardipine]]
 +
**PO: 20-40mg q8hr, or 30-60mg (extended release) q12hr
 +
**IV: 5mg/hr by slow infusion (50ml/hr), titrate to maximum of 30mg/hr, then maintenance of 2.0 - 15.5mg/hr
 +
*[[Clevidipine]]: 1-2 mg IV per hour
  
Amlodipine: 2.5- 20 (10) qD
+
==See Also==
 +
*[[Calcium Channel Blocker Toxicity]]
  
[[Category:Cards]]
+
[[Category:Cardiology]]
[[Category:Drugs]]
+
[[Category:Pharmacology]]

Latest revision as of 03:53, 6 March 2021

Ca Blocker BP/SVR HR SA/AV CF ION
Nifedipine +++ + - + -
Diltiazem ++ - + + -
Verapamil + -- ++ + -
Bepiridil +++ (-) min. +++ -
Amlodipine +++ + +
Felodipine + +
Nicardipine
Clevidipine

CF = coronary flow, ION = ionotropy, SA/AV = nodes

Doses:

  • Nifedipine
    • 10-30mg tid (Adalat CC: 30-90mg qD)
  • Diltiazem
    • 60-120 TID (CD: 180-360mg qD)
  • Verapamil: 80- 120mg TID
  • Bepiridil: 200-400mg QD
  • Amlodipine: 2.5- 20mg (10) qD
  • Nicardipine
    • PO: 20-40mg q8hr, or 30-60mg (extended release) q12hr
    • IV: 5mg/hr by slow infusion (50ml/hr), titrate to maximum of 30mg/hr, then maintenance of 2.0 - 15.5mg/hr
  • Clevidipine: 1-2 mg IV per hour

See Also