Calcium channel blockers: Difference between revisions

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{| class="wikitable"
{| {{table}}
| align="center" style="background:#f0f0f0;"|'''Ca Blocker'''
| align="center" style="background:#f0f0f0;"|'''BP/SVR'''
| align="center" style="background:#f0f0f0;"|'''HR'''
| align="center" style="background:#f0f0f0;"|'''SA/AV'''
| align="center" style="background:#f0f0f0;"|'''CF'''
| align="center" style="background:#f0f0f0;"|'''ION'''
|-
|-
| '''Ca Blocker'''
| [[Nifedipine]]||+++||+||-||+||-
| '''BP/SVR'''
| '''HR'''
| '''SA/AV'''
| '''CF'''
| '''ION'''
|-
|-
| [[Nifedipine]]
| [[Diltiazem]]||++||-||+||+||-
| +++
| +
| -
| +
| -
|-
|-
| [[Diltiazem]]
| [[Verapamil]]||+||--||++||+||-
| ++
| -
| +
| +
| -
|-
|-
| [[Verapamil]]
| [[Bepiridil]]||+++||(-)||min.||+++||-
| ++
| --
| ++
| +
| -
|-
|-
| [[Bepiridil]]
| [[Amlodipine]]||+++||+||+||||
| +
| (-)
| min.
| +++
| -
|-
|-
| [[Amlodipine]]
| [[Felodipine]]||||+||+||||
| +++
| +
| +
|  
|  
|-
|-
| [[Felodipine]]
| [[Nicardipine]]||||||||||
| +++
| +
| +
|  
|  
|-
|-
| [[Nicardipine]]
| [[Clevidipine]]||||||||||
|  
|  
|  
|  
|  
|}
|}


''CF = coronary flow, ION = ionotropy, SA/AV = nodes''
''CF = coronary flow, ION = ionotropy, SA/AV = nodes''


== Doses: ==
==Doses:==
*[[Nifedipine]]
*[[Nifedipine]]
**10-30 tid (Adalat CC: 30-90 qD)
**10-30 tid (Adalat CC: 30-90 qD)
*[[Diltiazem]]
*[[Diltiazem]]
**60-120 TID (CD: 180-360 qD)
**60-120 TID (CD: 180-360 qD)
*[[Verapamil]]: 80- 120 TID
*[[Verapamil]]: 80- 120mg TID
*[[Bepiridil]]: 200-400 QD
*[[Bepiridil]]: 200-400mg QD
*[[Amlodipine]]: 2.5- 20 (10) qD
*[[Amlodipine]]: 2.5- 20mg (10) qD
*[[Nicardipine]]
*[[Nicardipine]]
**PO: 20-40mg q8hr, or 30-60mg (extended release) q12hr
**IV: 5mg/hr by slow infusion (50ml/hr), titrate to maximum of 30mg/hr, then maintenance of 2.0 - 15.5mg/hr
*[[Clevidipine]]: 1-2 mg IV per hour


==See Also==
==See Also==

Revision as of 17:38, 20 September 2019

Ca Blocker BP/SVR HR SA/AV CF ION
Nifedipine +++ + - + -
Diltiazem ++ - + + -
Verapamil + -- ++ + -
Bepiridil +++ (-) min. +++ -
Amlodipine +++ + +
Felodipine + +
Nicardipine
Clevidipine

CF = coronary flow, ION = ionotropy, SA/AV = nodes

Doses:

  • Nifedipine
    • 10-30 tid (Adalat CC: 30-90 qD)
  • Diltiazem
    • 60-120 TID (CD: 180-360 qD)
  • Verapamil: 80- 120mg TID
  • Bepiridil: 200-400mg QD
  • Amlodipine: 2.5- 20mg (10) qD
  • Nicardipine
    • PO: 20-40mg q8hr, or 30-60mg (extended release) q12hr
    • IV: 5mg/hr by slow infusion (50ml/hr), titrate to maximum of 30mg/hr, then maintenance of 2.0 - 15.5mg/hr
  • Clevidipine: 1-2 mg IV per hour

See Also

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