CMV colitis: Difference between revisions

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==Differential Diagnosis==
==Differential Diagnosis==
*Bacterial Gastroenteritis
{{Colitis DDX}}
*Campylobacter Infections
*Clostridium Difficile Colitis
*Colon Cancer
*Crohn Disease
*Cryptosporidiosis
*Mycobacterium Avium-Intracellulare
*Toxic Megacolon
*Ulcerative Colitis
*Viral Gastroenteritis


{{CMV types}}
{{CMV types}}

Revision as of 13:17, 4 August 2015

Background

  • CMV is part of the Herpesviridae family
  • 50-80% of the world's population is seropositive for CMV
  • Causes a mild or undetectable infection in immunocompetent hosts
  • Severe systemic illness is found in immunosuppressed hosts

Clinical Presentation

  • Fever
  • Anorexia
  • Malaise
  • Weight loss
  • Dehydration
  • Abdominal pain
  • Abdominal distention
  • Nausea
  • Vomiting
  • Chronic watery diarrhea
  • Bloody diarrhea
  • Constipation
  • Worsening symptoms of inflammatory bowel disease

Differential Diagnosis

Colitis

CMV Diseases

Diagnosis

Management

Disposition

  • Ganciclovir 5mg/kg IV q12hrs x 21 days (or until resolution of symptoms)
  • Foscarnet 90mg/kg IV q12hrs daily x 21 days (or until resolution of symptoms)

See Also

External Links

References