Difference between revisions of "Blood products"

(Created page with "==PRBCs== Usual Dose: 1 U of PRBCs (250 mL or 3 mL/kg in peds) --> incr Hgb ~1.0 Indications (by Hb): Normal (rarely if >10; almost always if <6) Critically ill, otherwise h...")
 
Line 1: Line 1:
 
==PRBCs==
 
==PRBCs==
 
+
#Usual Dose: 1 U of PRBCs (250 mL or 3 mL/kg in peds) --> incr Hgb ~1.0
 
+
#Indications (by Hb):
Usual Dose: 1 U of PRBCs (250 mL or 3 mL/kg in peds) --> incr Hgb ~1.0
+
#Normal (rarely if >10; almost always if <6)
 
+
#Critically ill, otherwise healthy (keep > 7-9)
Indications (by Hb):
+
#Ischemic heart dz/critically ill age >65 (keep >10)
 
 
Normal (rarely if >10; almost always if <6)
 
 
 
Critically ill, otherwise healthy (keep > 7-9)
 
 
 
Ischemic heart dz/critically ill age >65 (keep >10)
 
 
 
 
  
 
==FFP==
 
==FFP==
 
+
#Usual Dose: 10-20 ml/kg (average adult = 3-6 units)
 
+
#2 U of FFP (450 mL) should correct most early coagulopathies
Usual Dose: 10-20 ml/kg (average adult = 3-6 units)
+
#An INR of 2.0 correlates w/ PT 1.5 times nl
 
 
*2 U of FFP (450 mL) should correct most early coagulopathies
 
 
 
*An INR of 2.0 correlates w/ PT 1.5 times nl
 
  
 
Indications:
 
Indications:
 
+
# Active bleeding AND PT/PTT >1.5 times nl (INR >2.0)
1) Active bleeding AND PT/PTT >1.5 times nl (INR >2.0)
+
# INR >20.0
 
+
# Massive PRBC transfusion (>9 U)
2) INR >20.0
+
# DIC not corrected by cryo.
 
+
# Coumadin overdose AND life threat bleed/invasive procedure
3) Massive PRBC transfusion (>9 U)
 
 
 
4) DIC not corrected by cryo.
 
 
 
5) Coumadin overdose AND life threat bleed/invasive procedure
 
 
 
 
  
 
==Platelets==
 
==Platelets==
 
+
#Usual Dose: 1 U per 10kg (~6-10 U) --> incr plat ~25,000.
 
+
#1 U (25-50 mL = "6-pack") --> incr plat 5-10,000 (adult) or 20,000 (20 kg child)
Usual Dose: 1 U per 10kg (~6-10 U) --> incr plat ~25,000.
+
#Indications: See "HEME: Thrombocytopenia"
 
 
*1 U (25-50 mL = "6-pack") --> incr plat 5-10,000 (adult) or 20,000 (20 kg child)
 
 
 
*Indications: See "HEME: Thrombocytopenia"
 
 
 
 
  
 
==Risks==
 
==Risks==
 
+
#Hep B ~1:100,000
 
+
#Hep C ~1:1 million
Hep B ~1:100,000
+
#HIV 1:2 million
 
 
Hep C ~1:1 million
 
 
 
HIV 1:2 million
 
 
 
 
  
 
==Source ==
 
==Source ==
 
 
 
2/18/06 DONALDSON (addapted from Rosen, Lampe, Charfen)
 
2/18/06 DONALDSON (addapted from Rosen, Lampe, Charfen)
 
 
 
  
 
[[Category:Heme/Onc]]
 
[[Category:Heme/Onc]]

Revision as of 13:29, 15 March 2011

PRBCs

  1. Usual Dose: 1 U of PRBCs (250 mL or 3 mL/kg in peds) --> incr Hgb ~1.0
  2. Indications (by Hb):
  3. Normal (rarely if >10; almost always if <6)
  4. Critically ill, otherwise healthy (keep > 7-9)
  5. Ischemic heart dz/critically ill age >65 (keep >10)

FFP

  1. Usual Dose: 10-20 ml/kg (average adult = 3-6 units)
  2. 2 U of FFP (450 mL) should correct most early coagulopathies
  3. An INR of 2.0 correlates w/ PT 1.5 times nl

Indications:

  1. Active bleeding AND PT/PTT >1.5 times nl (INR >2.0)
  2. INR >20.0
  3. Massive PRBC transfusion (>9 U)
  4. DIC not corrected by cryo.
  5. Coumadin overdose AND life threat bleed/invasive procedure

Platelets

  1. Usual Dose: 1 U per 10kg (~6-10 U) --> incr plat ~25,000.
  2. 1 U (25-50 mL = "6-pack") --> incr plat 5-10,000 (adult) or 20,000 (20 kg child)
  3. Indications: See "HEME: Thrombocytopenia"

Risks

  1. Hep B ~1:100,000
  2. Hep C ~1:1 million
  3. HIV 1:2 million

Source

2/18/06 DONALDSON (addapted from Rosen, Lampe, Charfen)