Bleeding treatments: Difference between revisions

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==Treatments==
==Treatments==
#pRBCs
#[[Packed_red_blood_cells|Packed Red Blood Cells]]
#DDAVP 0.3mg/kg subQ or IV (max 20mg)
#[[DDAVP]] 0.3mg/kg subQ or IV (max 20mg)
#Platelets
#[[Platelet transfusion|Platelets]]
#FFP
#[[Fresh frozen plasma|FFP]]
#Cryopreticipate
#[[Cryoprecipitate]]
#Vitamin K (10mg SQ/IM)
#[[Vitamin_K|Vitamin K (10mg SQ/IM)]]
#Protamine (Heparin)
#[[Unfractionated_heparin_reversal|Protamine (Heparin reversal)]]
#Estrogen (Uterine, renal)
#Estrogen (Uterine, renal)
#PPI/Pepcid/Octreotide (GI)
#[[PPI]]/[[famotidine]]/[[octreotide]] ([[GI bleed|GI]])
 
#[[Quick_Clot_(Kaolin)|Quick Clot (Topical)]]
==Vitamin K Deficiency==
#[[TXA]]
#FFP
#Vitamin K (+/- takes 24hrs to affect & 2wk to wear off)
 
==Warfarin==
*See [[Warfarin (Coumadin) Reversal]]
 
==Heparin/Lovenox==
#Protamie (1mg IV Q100 U of heparin in previous 4hrs)
#Massive bleed --> cryoprecipitate (10 U IV), then FFP (& platelets, aminocaproic acid infusion if nec)
 
==Liver Disease==
See [[Coagulation Disorders]]
 
==Renal Disease==
See [[Coagulation Disorders]]
 
==DIC==
See [[DIC]]
 
==Factor VIII Inhibitor==
(PTT does not correct after mixing)
 
#high dose Factor VII, prothrombin, or recombinant factor VIIa
 
==Lupus Anticoagulant==
(rare)
 
#warfarin or ASA


==See Also==
==See Also==
*[[Hemophilia]]
*[[Coagulopathy (Main)]]
 
*[[Hemorrhage]]
==Source ==
*[[Blood products]]
1/22/06 DONALDSON (adapted from Tintinalli's)
*[[Massive transfusion]]


==References==
<references/>
[[Category:Heme/Onc]]
[[Category:Heme/Onc]]

Latest revision as of 15:30, 27 January 2022