Bleeding treatments: Difference between revisions

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==Treatments==
==Treatments==
#pRBCs
#[[Packed_red_blood_cells|Packed Red Blood Cells]]
#DDAVP 0.3mg/kg subQ or IV (max 20mg)
#[[DDAVP]] 0.3mg/kg subQ or IV (max 20mg)
#Platelets
#[[Platelet transfusion|Platelets]]
#FFP
#[[Fresh frozen plasma|FFP]]
#Cryopreticipate
#[[Cryoprecipitate]]
#Vitamin K (10mg SQ/IM)
#[[Vitamin_K|Vitamin K (10mg SQ/IM)]]
#Protamine (Heparin)
#[[Unfractionated_heparin_reversal|Protamine (Heparin reversal)]]
#Estrogen (Uterine, renal)
#Estrogen (Uterine, renal)
#PPI/Pepcid/Octreotide (GI)
#[[PPI]]/[[famotidine]]/[[octreotide]] ([[GI bleed|GI]])
#[[Quick_Clot_(Kaolin)|Quick Clot (Topical)]]
#[[TXA]]


==Warfarin/Vitamin K Deficiency==
==See Also==
#FFP
*[[Coagulopathy (Main)]]
#Vitamin K (+/- takes 24hrs to affect & 2wk to wear off)
*[[Hemorrhage]]
 
*[[Blood products]]
==Heparin/Lovenox==
*[[Massive transfusion]]
#Protamie (1mg IV Q100 U of heparin in previous 4hrs)
#Massive bleed --> cryoprecipitate (10 U IV), then FFP (& platelets, aminocaproic acid infusion if nec)
 
==Liver Disease==
#Vitamin K
#PPI/pepcid/octreotide (variceal bleed)
#FFP
#Plts
#DDAVP
 
==Renal Disease==
#pRBCs (<8 Hb)
#Hemodialysis
#DDAVP
#Conjugated estrogens (unknown mechanism)
#Cyroprecipitate & platelets (in life-threatening bleed only)
 
==DIC==
(see also DIC)
 
#IVF
#PRBCs
#Vitamin K
#Folate (1mg IV)
 
 
If bleeding predominant DIC:
#FFP (2 U at a time)
#Cryoprecipitate (10 bags at a time)
#(Heparin is contraversial in thrombosis predominant DIC)
 
==Factor VIII Inhibitor==
(PTT does not correct after mixing)
 
#high dose Factor VII, prothrombin, or recombinant factor VIIa
 
==Lupus Anticoagulant==
(rare)
 
#warfarin or ASA
 
==Source ==
1/22/06 DONALDSON (adapted from Tintinalli's)


==References==
<references/>
[[Category:Heme/Onc]]
[[Category:Heme/Onc]]

Latest revision as of 15:30, 27 January 2022