Bacitracin

Revision as of 22:34, 11 October 2017 by Humanguy (talk | contribs) (Pharmacology: added excretion)

Administration

  • Type: Topical antibiotic
  • Dosage Forms: ointment
  • Dosage strengths: 500 unit/g
  • Routes of Administration: topical, ophthalmic, IM
  • Common Trade Names: BACiiM, Baciguent, Bacitracin Ophthalmic Ointment

Adult Dosing

  • Apply to wound 2-5 times per day

Pediatric Dosing

  • Apply to wound 2-5 times per day
  • Staph pneumonia/empyema known to be susceptible to bacitracin: 900-1000 units/kg/day IM in 2 to 3 divided doses

Special Populations

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

  • Renal toxicity (IM only)

Common

  • Contact dermatitis

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion: Urine 10-40%

Mechanism of Action

  • Interferes with cell wall peptidoglycan activity
  • Active against staph

Comments

See Also

References