Bacitracin: Difference between revisions
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==Administration== | ==Administration== | ||
*Type: | *Type: Topical antibiotic | ||
*Dosage Forms: | *Dosage Forms: ointment | ||
*Routes of Administration: | *Routes of Administration: topical, IM | ||
*Common Trade Names: | *Common Trade Names: | ||
==Adult Dosing== | ==Adult Dosing== | ||
*Apply to wound 2-5 times per day | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
*Apply to wound 2-5 times per day | |||
*Staph pneumonia/empyema known to be susceptible to bacitracin: 900-1000 units/kg/day IM in 2 to 3 divided doses | |||
==Special Populations== | ==Special Populations== | ||
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: | *[[Drug Ratings in Pregnancy|Pregnancy Rating]]: C | ||
*[[Lactation risk categories|Lactation risk]]: | *[[Lactation risk categories|Lactation risk]]: Infant risk minimal | ||
*Renal: no adjustment | |||
*Hepatic: No adjustment | |||
* | |||
==Contraindications== | ==Contraindications== | ||
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==Adverse Reactions== | ==Adverse Reactions== | ||
===Serious=== | ===Serious=== | ||
*Renal toxicity (IM only) | |||
===Common=== | ===Common=== | ||
*Contact dermatitis | |||
==Pharmacology== | ==Pharmacology== | ||
*Half-life: | *Half-life: | ||
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==Mechanism of Action== | ==Mechanism of Action== | ||
*Interferes with cell wall peptidoglycan activity | |||
*Active against staph | |||
==Comments== | ==Comments== | ||
Revision as of 15:49, 7 September 2016
Administration
- Type: Topical antibiotic
- Dosage Forms: ointment
- Routes of Administration: topical, IM
- Common Trade Names:
Adult Dosing
- Apply to wound 2-5 times per day
Pediatric Dosing
- Apply to wound 2-5 times per day
- Staph pneumonia/empyema known to be susceptible to bacitracin: 900-1000 units/kg/day IM in 2 to 3 divided doses
Special Populations
- Pregnancy Rating: C
- Lactation risk: Infant risk minimal
- Renal: no adjustment
- Hepatic: No adjustment
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Renal toxicity (IM only)
Common
- Contact dermatitis
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
Mechanism of Action
- Interferes with cell wall peptidoglycan activity
- Active against staph