Bacitracin: Difference between revisions
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*Type: Topical antibiotic | *Type: Topical antibiotic | ||
*Dosage Forms: ointment | *Dosage Forms: ointment | ||
*Routes of Administration: topical, IM | *Dosage strengths: 500 unit/g | ||
*Common Trade Names: | *Routes of Administration: topical, ophthalmic, IM | ||
*Common Trade Names: BACiiM, Baciguent, Bacitracin Ophthalmic Ointment | |||
==Adult Dosing== | ==Adult Dosing== | ||
Revision as of 22:32, 11 October 2017
Administration
- Type: Topical antibiotic
- Dosage Forms: ointment
- Dosage strengths: 500 unit/g
- Routes of Administration: topical, ophthalmic, IM
- Common Trade Names: BACiiM, Baciguent, Bacitracin Ophthalmic Ointment
Adult Dosing
- Apply to wound 2-5 times per day
Pediatric Dosing
- Apply to wound 2-5 times per day
- Staph pneumonia/empyema known to be susceptible to bacitracin: 900-1000 units/kg/day IM in 2 to 3 divided doses
Special Populations
- Pregnancy Rating: C
- Lactation risk: Infant risk minimal
- Renal: no adjustment
- Hepatic: No adjustment
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Renal toxicity (IM only)
Common
- Contact dermatitis
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
Mechanism of Action
- Interferes with cell wall peptidoglycan activity
- Active against staph