Aortic stenosis

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Background

Clinical Features

  • Dyspnea, CP, syncope
    • Once symptoms present mean surival is 2-3yr
  • ejection systolic murmur radiating to carotids
  • Pulsus parvus et tardus, slow to rise and late peaking
  • Narrowed pulse pressure
  • Soft 2nd heart sound

Differential Diagnosis

Valvular Emergencies

Diagnosis

  • Echocardiography, transthoracic
    • This will typically demonstrate minimal excursion of the aortic valve leaflet
    • Continuous wave doppler across the aortic valve with typically demonstrate high velocities
    • Color doppler will demonstrate turbulent flow across the valve
    • The left ventricle will demonstrate left ventricular hypertrophy
  • Severity by CW Doppler velocity (m/s)[1]
    • Ensure parallel intercept angle across aortic valve in apical view
    • <2.5 = aortic sclerosis
    • 2.6 - 2.9 = mild
    • 3.0 - 4.0 = moderate
    • >4.0 = severe

Treatment

  • Avoid negative inotropes such as BBs, CCBs
  • Afterload reduction is controversial and in decompensated AS should only be conducted in a monitored setting
    • Consider cards consult
  • AS + A-fib = emergency
    • Consider emergent cardioversion
  • Pulm edema
    • Diuretics, intubation if necessary
    • Extreme caution with use of nitrates/vasodilators
  • In critical cases, particularly in those unstable to undergo emergent surgery, balloon aortic valvuloplasty may be an option.

Disposition

See Also

References

  1. Baumgartner H, Hung J, Bermejo J, Chambers JB, Evangelista A, Griffin BP, Iung B, Otto CM, Pellikka PA, Quiñones M, American Society of Echocardiography, and European Association of Echocardiography. Echocardiographic assessment of valve stenosis: EAE/ASE recommendations for clinical practice. J Am Soc Echocardiogr. 2009 Jan;22(1):1-23; quiz 101-2.