Ammonia toxicity

Background

  • Route of exposure:
    • Inhalation of ammonia may cause nasopharyngeal and tracheal burns, bronchiolar and alveolar edema, and airway destruction resulting in respiratory distress or failure.
    • Skin/Eye Contact - the extent of injury produced by exposure to ammonia depends on the duration of the exposure and the concentration of the gas or liquid. Contact with concentrated ammonia solutions, such as some industrial cleaners (25%), may cause serious corrosive injury, including skin burns, permanent eye damage, or blindness. The full extent of damage to the eyes may not be clear until up to 1 week after the injury is sustained. Contact with liquefied ammonia can cause frostbite injury.
    • Ingestion - ingestion of ammonium hydroxide, while uncommon, results in corrosive damage to the mouth, throat, and stomach. Ingestion of ammonia does not normally result in systemic poisoning.

Clinical Features

Differential Diagnosis

Evaluation

Management

Disposition

See Also

External Links

References