Adjusting mechanical ventilation settings

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O2

  • PaO2 - wean O2 for a goal PaO2 >60 mmHg
  • FiO2 - wean to < 50% if possible while maintaining adequate PaO2
  • PEEP - refer to ARDSnet protocol to avoid barotrauma

paCO2

  • Mainly affected by Tidal volume and RR
  • VE = minute ventilation (RR x TV)

pH

  • For every increase or decrease in PaCO2, pH changes accordingly by 0.008
  • For every increase or decrease in HCO3 pH changes accordingly by 0.015

See Also

Mechanical Ventilation Pages

References